Spring Valley Laboratory facilities consist of 24,000 square feet of animal housing, support, and laboratory space securely situated in a one hundred acre campus.  There is conventional (8,000 sq. ft.) and specific pathogen free (14,000 square feet) of housing and support space for mice, rats, rabbits, guinea pigs, ferrets, hamsters, and mini pigs as well as a barn for housing sheep, goats and other large animals,.  Support spaces include a surgical suite with recovery room, intensive care area, designated test article storage and preparation areas, laboratories for clinical pathology, specimen analysis, necropsy, pathology, and secure access-controlled archives.  Quarterly health screening is performed for all species in the SPF facility.  Animals may be transferred to SVL from other facilities with proof of acceptable health status.

A facility monitoring system continuously senses security status and environmental conditions as well as refrigerator, freezer, and incubator temperatures.  In the event of a power failure, an automatic backup electrical generator supplies all the electrical needs of the entire facility. Redundant HVAC systems automatically engage when needed.